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XBI vs. FBT: Broad Biotech Exposure or Concentrated Bets?

XBI's lower fees and 155-stock portfolio contrast sharply with FBT's concentrated 30-holding approach, though FBT has experienced less volatility over the past five years.

XBI vs. FBT: Broad Biotech Exposure or Concentrated Bets?

Published August 19, 2026 · Category: Finance

Overview

The State Street SPDR S&P Biotech ETF (NYSEMKT:XBI) provides broad exposure to the biotech industry, while the First Trust NYSE Arca Biotechnology Index Fund (NYSEMKT:FBT) offers a much more concentrated, equal-weighted alternative.

Biotech is a volatile sector often driven by clinical trial results and regulatory approvals. This comparison looks at how these two funds offer exposure to the space. While both focus on the same industry, they utilize different indexing methodologies that significantly impact their volatility and concentration risk.

Beta measures price volatility relative to the S&P 500; beta is calculated from monthly returns over the available fund history (up to five years). The 1-year return represents total return over the trailing 12 months. Dividend yield is the trailing-12-month distribution yield.

Details

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Source

Originally published at www.fool.com.

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Disclaimer: This article is for informational purposes only and does not constitute investment advice. Data may be delayed up to 15 minutes. Past performance is not indicative of future results. Consult a licensed financial advisor before making investment decisions.