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Better Pharma ETF: iShares IHE vs. State Street XPH

IHE concentrates 23.6% in Eli Lilly and delivers 1.4% yield, while XPH spreads risk across 62 holdings with a lower 0.35% expense ratio.

Better Pharma ETF: iShares IHE vs. State Street XPH

Published October 10, 2026 · Category: Finance

Overview

The iShares U.S. Pharmaceuticals ETF (NYSEMKT:IHE) offers a concentrated, market cap-weighted approach to drugmakers, while the State Street SPDR S&P Pharmaceuticals ETF (NYSEMKT:XPH) provides broader, more equal-weighted exposure to the domestic pharmaceutical industry.

Both funds provide targeted exposure to the U.S. pharmaceutical industry, yet this comparison shows that their internal mechanics lead to very different risk profiles. While the iShares U.S. Pharmaceuticals ETF leans heavily into the largest players in the sector, the State Street SPDR S&P Pharmaceuticals ETF spreads its assets across a wider range of companies.

Details

Beta measures price volatility relative to the S&P 500; beta is calculated from monthly returns over the available fund history (up to five years). The 1-year return represents total return over the trailing 12 months. Dividend yield is the trailing-12-month distribution yield.

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Source

Originally published at www.fool.com.

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Disclaimer: This article is for informational purposes only and does not constitute investment advice. Data may be delayed up to 15 minutes. Past performance is not indicative of future results. Consult a licensed financial advisor before making investment decisions.